yvgJ [2019-06-12 10:10:15]

lipoteichoic acid synthesis primase

Locus: BSU33360

Isoelectric point: 5.31

Molecular weight: 70.57 kDa

Protein length: 617 aa

Gene length: 1854 bp

Function: biosynthesis of lipoteichoic acid

Product: lipoteichoic acid synthesis primase

Essential: no

Synonyms: yvsF

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Cell envelope and cell division → Cell wall synthesis → Biosynthesis of lipoteichoic acid
• Metabolism → Additional metabolic pathways → Biosynthesis of cell wall components → Biosynthesis of lipoteichoic acid
• Groups of genes → Membrane proteins

Gene

Coordinates: 3,422,354 3,424,207

The protein

Protein family

• LTA synthase family (according to Swiss-Prot)

Paralogous protein(s)

• YfnI, YqgS, LtaS

Modification

• can be phosphorylated by PrkC in vitro PubMed

Structure

• 2W5Q (LtaS from S. aureus, corresponds to aa 215 ... 615 of YvgJ) PubMed

Localization

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operons

• Genes: yvgJ
  Description: PubMed

Biological materials

Mutant

• MGNA-B065 (yvgJ::erm), available at the NBRP B. subtilis, Japan
• BKE33360 (yvgJ::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCAATATGACTCCTCACG, downstream forward: _UP4_TGAAAAAATCCCTCTATCAA
• BKK33360 (yvgJ::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCAATATGACTCCTCACG, downstream forward: _UP4_TGAAAAAATCCCTCTATCAA

References

Reviews

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Original publications

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